An Indole Alkaloid from the Fruiting Body of Boletus umbriniporus

Yoon-Ju Lee   Byung-Soon Hwang   Ja-Gyeong Song   Dae-Won Kim   E-Eum Woo   In-Kyoung Lee   Bong-Sik* Yun   


ABSTRACT : Mushrooms are valued as a nutritional food and also as an important source of useful medicinal components. They produce various secondary metabolites which have interesting biological activities and unique chemical structures. As part of our ongoing investigation on chemical constituents and bioactive components of Korean native mushrooms, compound 1, an indole alkaloid, was isolated from the fruiting body of Boletus umbriniporus. B. umbriniporus is characterized by its yellow flesh, which changes to pallid blue when exposed to air, and its chemical constituent has not been reported. Chemical structure of compound 1 was determined to be flazin on the basis of ESI-mass, 1H NMR, 13C NMR, 1H-1H COSY, HMQC, and HMBC analysis. This compound was isolated from the fruiting body of B. umbriniporus for the first time.


This work was supported by a grant from the Korea Forest Service, Republic of Korea.

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