Korean Journal of Mycology (Kor. J. Mycol.)
Hee-Wan Kang 1,2*, Man Hyee Lee 3 and Geon-Sik Seo 4
1Graduate School of Future Convergence Technology, Hankyong National University, Ansung 456-749, Korea
2Institute of Genetic engineering, Hankyong National University, Ansung 456-749, Korea
3College of Veterinary Medicine, Gyeongpuk National Univ., Daegu 702-701, Korea
4Korea National College of Agricultural and Fisheries, Bongdam, Hwaseong 445-760, Korea
Correspondence to kanghw2@hknu.ac.kr
Korean Journal of Mycology (Kor J Mycol) December 30, 2013, 41(4):243-247.
https://doi.org/10.4489/KJM.2013.41.4.243
Received: October 22, 2013; Revised: October 23, 2013; Accepted: October 23, 2013
Published: December 30, 2013.
© The Korean Society of Mycology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Novel Phellinus linteus HN1009K (HK1009) has been characterized on speedy mycelial growth and yearly artificial cultivation. In this study, antioxidant and anti-inflammatory activities of ethanol extract from mycelium and fruiting body of P. linteus HN1009K (HK1009) were compared to those of P. linteus (PL, Korea Sangwhang) and P. baumii (PB, Jangsu Sanghwang) as controls. HK1009 extract showed higher DPPH free radical scavenging activity in both mycelial and fruiting body samples than those of PL and PB. However, in xanthine oxidase assay, antioxidant effect was highly measured on mycelial samples of PL and HK1009. Mycelial extract of HK1009 induced high inhibitory effect on LPS-induced nitric oxide (NO) production in RAW264.7 cells comparing to PL and PB without toxicity on the cells. The results suggest that P. linteus HN1009K possesses superior antioxidant activity and anti-inflammatory effects.
Antioxidant and anti-inflammatory activities, Phellinus linteus HN1009K