Korean Journal of Mycology (Kor. J. Mycol.)
Ja-Won Shin 1, Sang-Min Bae 1, Sang-Min Han 1, Yun-Hae Lee 2, Youn-Kyung Jeong 2, Jeong-Hyun Ji 2 and Jong- Soo Lee 1*
1Department of Biomedicinal Science and Biotechnology, Paichai University, Daejeon 35345, Korea
2Mushroom Research Station, Gyeonggi-do Agricultural Research & Extension Service, Gwangju 12805, Korea
Correspondence to biotech8@pcu.ac.kr
Korean Journal of Mycology (Kor J Mycol) March 31, 2016, 44(1):57-60.
https://doi.org/10.4489/KJM.2016.44.1.57
Received: January 18, 2016; Revised: March 8, 2016; Accepted: March 9, 2016
Published: March 31, 2016.
© The Korean Society of Mycology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Following preparation of water extracts of Pleurotus cornucopiae fruiting body-containing α-glucosidase inhibitor, their antihyperglycemic effects were examined using streptozotocin-induced diabetic Sprague-Dawley (SD)-rats. The water extracts from Pleurotus cornucopiae showed dosage-dependant antihyperglycemic effects on the streptozotocin-induced diabetic SD-rats after oral administration to 120 min on the short time test and 4 days on the long time test, respectively. The water extracts from Pleurotus cornucopiae fruiting body showed dosage-dependent hypoglycemic action after administration to 120 min and 4 days in the SD-rat and streptozotocin-induced diabetic SD-rat.
Antihyperglycemic effects, α-Glucosidase inhibitor, Pleurotus cornucopiae, Water extracts