Korean Journal of Mycology (Kor. J. Mycol.)
Min-Gu Kang 1, Ha-Kun Kim 1*, Sung-Hun Yi 2, Sung-Il Lim 2 and Jong-Soo Lee 1
1Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea
2Korea Food Research Institute, Seongnam 463-746, Korea
Correspondence to hakun@pcu.ac.kr
Korean Journal of Mycology (Kor J Mycol) December 1, 2011, 39(3):194-197.
https://doi.org/10.4489/KJM.2010.39.3.194
(Received 8, November 2011., Accepted 14, November 2011)
Published: December 1, 2011.
© The Korean Society of Mycology
Forty eight strains of yeast were cultured in potato dextorse(PD) broth at 30 oC for 24 hr and centrifuged with 12,000 rpm for 20 min. After concentrated the cultures, antihypertensive angiotensin I-converting enzyme(ACE) inhibitory activities of its concentrates were investigated. Among them, the concentrates from Saccharomyces cerevisiae Y183-3 showed the highest ACE inhibitory activity of 71.8%. The ACE inhibitor from Saccharomyces cerevisiae Y183-3 was maximally produced when Saccharomyces cerevisiae Y183-3 cultured in PD broth at 30 oC for 36 hr.
Antihypertensive angiotensin I-converting enzyme inhibitor, Potato dextrose broth, Saccharomyces cerevisiae Y183-3