Physiological Activities of Water Extract and Solvent Fractions of an Edible Mushroom, Pholiota adiposa

Jun-Ho Kim   


This study was conducted in order to investigate the physiological activities, including antioxidative, fibrinolytic, thrombin inhibitory, and α -glucosidase inhibitory activities of the water extract and solvent fractions isolated from Pholiota adiposa. The antioxidative activities of the water extract and water fraction were 57.57% and 48.27%, respectively. The fibrinolytic activity was strong only in the ethyl acetate fraction at 0.70 plasmin units/mL. The ethyl acetate fraction showed high thrombin inhibitory activity, and a-glucosidase inhibitory activity at 77.67% and 89.32%, respectively. The ethyl acetate fraction hydrolyzed both A α and B β subunits of human fibrinogen, but did not show reactivity for the γ form of human fibrinogen. Fibrinolytic activity of the ethyl acetate fraction was not decreased by heating for 10 min at 100ºC.


본 연구는 2013년도 상지대학교 교내연구비의 지원으로 이루어졌음을 밝히며 감사드립니다.

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